FireProt-ASR

Czech title

FireProt-ASR

Type

software

License

Use of the result by another entity is possible without acquiring a license in some cases

License Fee

The licensor does not require a license fee for the result

Authors

Musil Miloš, Ing., Ph.D. (DIFS)
Khan Rayyan
Beier Andy, Dr.
Štourač Jan (FIT)
Konegger Hannes
Damborský Jiří, prof. Mgr., Dr. (UMEL)
Bednář David (FIT)

Keywords

protein engineering, thermostable proteins, ancestral sequence reconstruction, evolutionary design, protein stability

Description

FireProt-ASR is a web server for an automated calculation of ancestral sequences. Fireprot-ASR allows users to perform ancestral sequence reconstruction starting from a single protein sequence. The pipeline first compiles a dataset of catalytically similar protein sequences, reduces the starting dataset to the required size, aligns them, construct their phylogenetic tree, and then reconstruct ancestral nodes together with the correction of the ancestral gaps. It also allows user to input their own data and start from a different point in the pipeline.

Location

Nástroj je dostupný na internetové adrese: http://loschmidt.chemi.muni.cz/fireprotasr

Projects

Nástroje, metody a technologie ICT pro podporu konceptu smart cities, BUT, Vnitřní projekty VUT, FIT-S-17-3964, 2017-2020, completed

Research groups

Information and Database Systems Research Group (RG IS)

Departments

Department of Information Systems (DIFS)