Publication Details

SeQuaiA: A Scalable Tool for Semi-Quantitative Analysis of Chemical Reaction Networks

ČEŠKA, M.; CHAU, C.; KŘETÍNSKÝ, J. SeQuaiA: A Scalable Tool for Semi-Quantitative Analysis of Chemical Reaction Networks. In International Conference on Computer Aided Verification. Lecture Notes in Computer Science. Cham: Springer Verlag, 2020. p. 653-666. ISBN: 978-3-030-53287-1.
Czech title
SeQuaiA: Nástroj pro semikvantitativní analýzu chemických reakčních sítí
Type
conference paper
Language
English
Authors
Češka Milan, doc. RNDr., Ph.D. (DITS)
CHAU, C.
KŘETÍNSKÝ, J.
URL
Keywords

probabilistic verification, population Markov chains, abstraction

Abstract

Chemical reaction networks (CRNs) play a fundamental role in analysis and design of biochemical systems. They induce continuous-time stochastic systems, whose analysis is a computationally intensive task. We present a tool that implements the recently proposed semi-quantitative analysis of CRN. Compared to the proposed theory, the tool implements the analysis so that it is more flexible and more precise. Further, its GUI offers a wide range of visualization procedures that facilitate the interpretation of the analysis results as well as guidance to refine the analysis. Finally, we define and implement a new notion of "mean" simulations, summarizing the typical behaviours of the system in a way directly comparable to standard simulations produced by other tools.

Published
2020
Pages
653–666
Proceedings
International Conference on Computer Aided Verification
Series
Lecture Notes in Computer Science
Volume
12224
ISBN
978-3-030-53287-1
Publisher
Springer Verlag
Place
Cham
DOI
UT WoS
000695276000032
EID Scopus
BibTeX
@inproceedings{BUT168142,
  author="ČEŠKA, M. and CHAU, C. and KŘETÍNSKÝ, J.",
  title="SeQuaiA: A Scalable Tool for Semi-Quantitative Analysis of Chemical Reaction Networks",
  booktitle="International Conference on Computer Aided Verification",
  year="2020",
  series="Lecture Notes in Computer Science",
  volume="12224",
  pages="653--666",
  publisher="Springer Verlag",
  address="Cham",
  doi="10.1007/978-3-030-53288-8\{_}32",
  isbn="978-3-030-53287-1",
  url="https://link.springer.com/chapter/10.1007/978-3-030-53288-8_32"
}
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