Product Details

FireProt-ASR

Created: 2019

Czech title
FireProt-ASR
Type
software
License
Use of the result by another entity is possible without acquiring a license in some cases
License Fee
The licensor does not require a license fee for the result
Authors
Musil Miloš, Ing., Ph.D. (DIFS)
Khan Rayyan
Beier Andy, Dr.
Štourač Jan
Konegger Hannes
Damborský Jiří, prof. Mgr., Dr. (UMEL)
Bednář David
Keywords

protein engineering, thermostable proteins, ancestral sequence reconstruction,
evolutionary design, protein stability

Description

FireProt-ASR is a web server for an automated calculation of ancestral
sequences. Fireprot-ASR allows users to perform ancestral sequence reconstruction
starting from a single protein sequence. The pipeline first compiles a dataset of
catalytically similar protein sequences, reduces the starting dataset to the
required size, aligns them, construct their phylogenetic tree, and then
reconstruct ancestral nodes together with the correction of the ancestral gaps.
It also allows user to input their own data and start from a different point in
the pipeline.

Location

Nástroj je dostupný na internetové adrese: http://loschmidt.chemi.muni.cz/fireprotasr

Projects
Nástroje, metody a technologie ICT pro podporu konceptu smart cities, BUT, Vnitřní projekty VUT, FIT-S-17-3964, start: 2017-03-01, end: 2020-02-29, completed
Research groups
Departments
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