Publication Details

Computational molecular evolution - from mathematical models to novel distance metric based on intra-group analysis

VOGEL, I.; OČENÁŠEK, P.; ZEDEK, F. Computational molecular evolution - from mathematical models to novel distance metric based on intra-group analysis. EDS '11 IMAPS CS International Conference Proceedings. Brno: Brno University of Technology, 2011. p. 264-269. ISBN: 978-80-214-4303-7.
Czech title
Výpočtová molekulární evoluce - od matematických modelů k novým vzdálenostním metrikám pracujících na základě vnitroskupinové analýzy
Type
conference paper
Language
English
Authors
Vogel Ivan, Ing., Ph.D.
Očenášek Pavel, Mgr. Ing., Ph.D. (DIFS)
Zedek František
Keywords

phylogeny, intra-group analysis, substitution model, Markov chains

Abstract

In the proposed paper we analyse and discuss the molecular evolution from the point of view of mathematical analysis and statistics. Some characteristics of distance-based algorithms for phylogenetic inference are depicted. We furthermore use knowledge of mathematical models to design a modified algorithm for phylogenetic tree reconstruction. We implement the presented methods in the form of a simple phylogenetic library, briefly report about results of our case study and finally show a way for building a web interface for biological purposes through Mobyle portal. Finally, we draw a conclusion and discuss possible future work on the project.

Published
2011
Pages
264–269
Proceedings
EDS '11 IMAPS CS International Conference Proceedings
ISBN
978-80-214-4303-7
Publisher
Brno University of Technology
Place
Brno
BibTeX 
@inproceedings{BUT76292,
  author="Ivan {Vogel} and Pavel {Očenášek} and František {Zedek}",
  title="Computational molecular evolution - from mathematical models to novel distance metric based on intra-group analysis",
  booktitle="EDS '11 IMAPS CS International Conference Proceedings",
  year="2011",
  pages="264--269",
  publisher="Brno University of Technology",
  address="Brno",
  isbn="978-80-214-4303-7"
}
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